Regulation of apoptosis by heat shock proteins
نویسندگان
چکیده
منابع مشابه
Heat shock proteins: essential proteins for apoptosis regulation
Many different external and intrinsic apoptotic stimuli induce the accumulation in the cells of a set of proteins known as stress or heat shock proteins (HSPs). HSPs are conserved proteins present in both prokaryotes and eukaryotes. These proteins play an essential role as molecular chaperones by assisting the correct folding of nascent and stress-accumulated misfolded proteins, and by preventi...
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Since the elucidation of their functions in protein folding and translocation, heat shock protein chaperones have been a target of research in all spheres of biomedicine. Within the last five years, research efforts have intensified, following the discovery of raised levels of heat shock protein (Hsp) expression in the brains of patients suffering from many neurodegenerative disorders, includin...
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ژورنال
عنوان ژورنال: IUBMB Life
سال: 2014
ISSN: 1521-6543
DOI: 10.1002/iub.1274